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Updated: Aug 17, 2026

A Mouse Model of Vascularized Heterotopic Spleen Transplantation for Studying Spleen Cell Biology and Transplant Immunity
Published on: June 11, 2019
[Can the injured spleen be preserved? Results of 20-year experiments]
Irén Mikó1, József Serfozo, János Kappelmayer
1Debreceni Egyetem, Orvos- és Egészségtudományi Centrum, Sebészeti Mutéttani Tanszék, Debrecen. imiko@jaguar.unideb.hu
Abstract:
Researches of different spleen salvaging techniques have begun in 1986 at our department. The early purpose was to develop new spleen preservation surgical techniques, such as spleen autotransplantation and spleen resection. Besides the morphological and radiological examinations we also performed different investigations including hemorheological, hemostaseological and immunological follow-up of the splenic function. From these parameters changes in red blood cell deformability and peripheral phagocyte activity could indicate the possible complications originated from the reduced splenic function. Recent paper takes a survey of these experiences.

