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Updated: Aug 17, 2026

Establishment of a Minimally Invasive Rat Model of Pulmonary Embolism Using Autologous Blood Clots
Published on: October 25, 2024
[Modern approach to treatment in pulmonary thromboembolism]
Marko Buksa1, Vjekoslav Gerc, Mirza Dilić
1Klinika za bolesti srca i reumatizma, KCU Sarajevo.
Abstract:
Pulmonary embolism (PE) and deep vein thrombosis (DVT), respectively venous thromboembolism (VIE), are relatively frequent diseases. Appropriate management of PE includes risk stratification, preventive and primary therapy. Appearance of the disease ranges from mild to severe, and rapid and accurate risk stratification is extremely important. So appropriate management can range from prevention of recurent PE with anticoagulant therapy alone in low risk patients, to clot disolution or embolectomy in high risk patients. Preventive therapy prevents recurent VTE including anticoagulant therapy with heparin (low molecular weight heparin-LWM or unfr actional UFH), direct thrombin inhibitors (DTI) or oral anticoagulants. Primary therapy includes thrombolitic therapy or embolectomy (catheter or surgical). Prevention DVT and VTE includes mechanical and pharmacological measures in internal medicine, in general, cancer and orthopedics surgery.
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