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Updated: Aug 7, 2026

The Use of Reverse Phase Protein Arrays (RPPA) to Explore Protein Expression Variation within Individual Renal Cell Cancers
Published on: January 22, 2013
Current clinical trials in renal cell carcinoma
Mitchell H Sokoloff1, Siamak Daneshmand, Christopher W Ryan
1Department of Surgery, Section of Urologic Oncology, Division of Urology and Renal Transplantation, Portland, OR 97239-3098, USA. guonc@ohsu.edu
Urologists are crucial in advancing kidney cancer treatment through clinical trials, especially in the adjuvant setting after nephrectomy. Future research will expand their role as new therapies emerge for renal cell carcinoma.
Area of Science:
- Urology
- Oncology
- Nephrology
Background:
- Renal cell carcinoma (kidney cancer) treatment is predominantly surgical.
- Urologists play a significant role in designing and conducting clinical trials for kidney cancer patients.
- Current urologic clinical trial efforts focus on the adjuvant setting for patients post-nephrectomy with high recurrence risk.
Purpose of the Study:
- To review key clinical trials for patients with kidney cancer.
- To highlight the evolving role of urologists in renal cell carcinoma research.
Main Methods:
- This is a review article.
- It synthesizes information from current clinical trials in renal cell carcinoma.
- Focuses on trials relevant to urologic surgical practice.
Main Results:
- Urologists are actively involved in kidney cancer clinical trials.
- The focus is on adjuvant therapy post-nephrectomy for high-risk patients.
- The involvement of urologists is expected to grow with new therapeutic agents.
Conclusions:
- Surgical management remains central to renal cell carcinoma treatment.
- Urologists are integral to advancing kidney cancer care through clinical trials.
- The scope of urologic involvement in clinical trials will expand as therapies evolve.
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