Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Current concepts in ocular surface reconstruction.

Murat Dogru1, Kazuo Tsubota

  • 1Tokyo Dental College, Chiba, Japan.

Seminars in Ophthalmology
|July 16, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Clinical backgrounds of postoperative keratoplasty patients with spontaneous wound dehiscence or gaps after suture removal.

Cornea·2014
Same author

Grading criteria for chronic ocular graft-versus-host disease: comparing the NIH eye score, Japanese dry eye score, and DEWS 2007 score.

Scientific reports·2014
Same author

Clinical and molecular characteristics of childhood-onset Stargardt disease.

Ophthalmology·2014
Same author

Fasting mitigates immediate hypersensitivity: a pivotal role of endogenous D-beta-hydroxybutyrate.

Nutrition & metabolism·2014
Same author

Functional visual acuity assessment of severe atopic keratoconjunctivitis.

Cornea·2014
Same author

Ocular surface reconstruction by cultivated epithelial sheet transplantation.

Cornea·2014
Same journal

Longitudinal Structural and Functional Trajectories Following Netarsudil Intensification or Surgical Escalation in Primary Open-Angle Glaucoma.

Seminars in ophthalmology·2026
Same journal

Maternal Diabetes Mellitus During Pregnancy as a Risk Factor for Congenital Nasolacrimal Duct Obstruction in the Offspring - a Large-Scale National Study.

Seminars in ophthalmology·2026
Same journal

Clinical Spectrum and Genetics of Ocular Manifestations in Muscle Eye Brain Disease: A Literature Review.

Seminars in ophthalmology·2026
Same journal

Port Delivery System Vs Monthly Ranibizumab in VEGF-Driven Macular Disease: A Systematic Review and Meta-Analysis.

Seminars in ophthalmology·2026
Same journal

Genome Wide Pleiotropic Analysis Reveals Shared Genetic Architecture and Pathological Basis Between Retinitis Pigmentosa and Relevant Ocular Comorbidities.

Seminars in ophthalmology·2026
Same journal

Does QuantiFERON-Positive Tubercular Serpiginous-Like Choroiditis Affect Retinal and Choroidal Structures Differently in Affected Eyes Compared to Fellow Eyes and Healthy Controls? A Comparative OCT and OCT-A Study.

Seminars in ophthalmology·2026
See all related articles

Severe ocular surface disease impacts limbal stem cells. Advances in treatments like amniotic membrane transplantation and stem cell procedures offer improved visual rehabilitation options for patients.

Area of Science:

  • Ophthalmology
  • Regenerative Medicine
  • Ocular Surface Disease

Background:

  • Limbal stem cell diseases are complex, varying in severity.
  • Evaluation requires assessing stem cell loss, conjunctival disease, inflammation, and other ocular surface factors.

Purpose of the Study:

  • To review indications, methods, and clinical outcomes of advanced ocular surface reconstruction techniques.
  • To provide an overview of current data on novel treatments for severe ocular surface disease.

Main Methods:

  • Literature review of ocular surface reconstruction procedures.
  • Analysis of clinical data for amniotic membrane transplantation and stem cell-based therapies.

Main Results:

  • Traditional methods like keratoplasty had limited long-term success due to epithelial instability.

Related Experiment Videos

  • Newer techniques such as cultivated stem cell sheets show promise in ocular surface reconstruction.

    • Conclusions:

    • Ocular surface reconstruction has advanced significantly, offering better outcomes.
    • Careful patient evaluation is crucial for selecting appropriate treatment strategies for limbal stem cell deficiency.