ST-segment elevation of electrocardiogram in a patient with Shoshin beriberi

Hiroaki Kawano1, Yuji Koide, Genji Toda

  • 1Department of Cardiovascular Medicine, Course of Medical and Dental Sciences, Graduate School of Biomedical Sciences, Nagasaki University, Sakamoto.

Insights

Shoshin beriberi, a severe thiamine deficiency, can mimic heart attacks with ST-segment elevation. Prompt thiamine treatment led to recovery, highlighting its importance in differential diagnosis for shock.

Area of Science:

  • Cardiology
  • Endocrinology
  • Nutritional Science

Background:

  • Shoshin beriberi is a critical manifestation of severe thiamine deficiency.
  • It can present with cardiovascular collapse and neurological symptoms.

Observation:

  • A 58-year-old male presented with shock and ST-segment elevation myocardial infarction (STEMI)-like electrocardiographic changes.
  • Coronary angiography revealed no significant coronary artery stenosis, ruling out typical ischemic heart disease.

Findings:

  • The patient's condition improved dramatically following intravenous thiamine administration.
  • This suggests that Shoshin beriberi was the underlying cause of the myocardial damage and ECG abnormalities.

Implications:

  • Shoshin beriberi should be considered in the differential diagnosis of patients presenting with shock and ST-segment elevation, especially when coronary artery disease is absent.
  • Early recognition and treatment with thiamine are crucial for favorable outcomes in Shoshin beriberi.
  • This case underscores the critical role of thiamine in cardiac metabolism and function.

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