Related Experiment Video
Updated: Aug 17, 2026

Ex Vivo OCT-Based Multimodal Imaging of Human Donor Eyes for Research into Age-Related Macular Degeneration
Published on: May 26, 2023
Two patients with different features of congenital optic disc anomalies in the two eyes
Yumi Suzuki1, Eriko Kawase, Sachiko Nishina
1Department of Ophthalmology, National Center for Child Health and Development, 2-10-1, Okura, Setagaya-ku, Tokyo, 157-8535, Japan.
Purpose:
Description of two patients, each with different features of congenital optic disc anomalies in the two eyes.
Methods:
Case report
Results:
Patient 1, a 3-month-old girl, showed retinochoroidal coloboma involving the optic nerve in the right eye and optic nerve hypoplasia in the left eye. Patient 2, a 5-month-old boy, showed retinal fold extending inferiorly in the right eye and optic disc coloboma in the left eye.
Conclusions:
Since in both cases coloboma was seen in one eye, the optic nerve hypoplasia or retinal fold in the fellow eye of these two patients may have been related to the timing of embryonic fissure opening or closing.
Related Concept Videos
Photoreceptors and Visual Pathways
Anatomy of the Eyeball
Glaucoma: Overview
Focusing of Light in the Eye