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[Heart valve prostheses in children with reference to 95 cases].
Summary
Pediatric heart valve replacement, primarily for rheumatic heart disease, showed excellent long-term outcomes with low mortality. Anticoagulant therapy reduced rare thromboembolic complications.
Area of Science:
- Pediatric Cardiology
- Cardiac Surgery
- Rheumatology
Context:
- Rheumatic heart disease is a significant cause of pediatric valvular heart disease.
- Surgical intervention is often necessary for severe pediatric heart valve disease.
- Starr-Edwards ball prostheses were commonly used for valve replacement in children.
Purpose:
- To evaluate the long-term outcomes of heart valve replacement in children.
- To assess the efficacy and safety of Starr-Edwards ball prostheses in pediatric patients.
- To analyze the impact of anticoagulant therapy on thromboembolic complications.
Summary:
- Ninety-five children (≤15 years) underwent heart valve replacement over 10 years, predominantly for rheumatic heart disease affecting the mitral valve.
- Operative mortality was low (3.2%), with excellent long-term results including symptom regression and normalization of hemodynamic pressures.
- Thromboembolic complications (5.5%) occurred only in patients not receiving anticoagulant therapy, highlighting its importance.
Impact:
- Demonstrates the effectiveness of heart valve replacement in improving pediatric patients' quality of life and long-term survival.
- Provides evidence for the benefits of anticoagulant therapy in preventing thromboembolic events post-surgery.
- Highlights the challenges of managing evolving rheumatic disease and tricuspid incompetence in pediatric cardiac surgery.