Related Experiment Video

Updated: Aug 17, 2026

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels
05:31

Noninvasive Sampling of Mucosal Lining Fluid for the Quantification of In Vivo Upper Airway Immune-mediator Levels

Published on: August 7, 2017

[Occurrence of atopy in asthmatic children]

Iwona Grzelewska-Rzymowska1, Anna Kowejsza, Małgorzata Górska-Ciebiada

  • 1Kierownik Kliniki Gruźlicy, Chorób i Nowotworów Płuc IMW Uniwersytetu Medycznego w Lodzi.

Pneumonologia I Alergologia Polska
|July 19, 2005
PubMed

Insights

Asthma in children is strongly linked to atopy, with 88% of cases showing an allergic background. Many also suffer from other allergic conditions like allergic rhinitis and atopic dermatitis.

Area of Science:

  • Pediatrics
  • Allergology
  • Immunology

Context:

  • Childhood asthma prevalence has risen significantly over the past 30 years.
  • Atopy is a recognized predisposing factor for asthma development.
  • Understanding the link between atopy and childhood asthma is crucial for effective management.

Purpose:

  • To investigate the prevalence of atopy in children diagnosed with asthma.
  • To assess the association between asthma and other allergic conditions in pediatric patients.
  • To identify common allergens contributing to atopy in asthmatic children.

Summary:

  • A study examined 24 children (3-7 years) with asthma and 26 with bronchitis.
  • Methods included allergic history, skin prick tests, IgE levels, eosinophil counts, and spirometry.
  • Results indicated an atopic background in 88% of asthmatic children, with allergic rhinitis and atopic dermatitis being most common. Sensitization to house dust, house dust mites, and grass pollen was prevalent. Atopic features were also observed in children with recurrent bronchitis.

Impact:

  • Highlights the significant role of atopy in childhood asthma, informing diagnostic and therapeutic strategies.
  • Suggests a need for comprehensive allergy screening in children with asthma and recurrent respiratory issues.
  • Provides data on common allergen sensitization patterns in pediatric asthma, aiding in environmental control recommendations.

Related Concept Videos

Asthma I: Introduction01:28

Asthma I: Introduction

Asthma is a chronic inflammatory disorder of the airways characterized by variable airflow obstruction and heightened bronchial responsiveness to a wide range of triggers. The underlying inflammation leads to airway swelling, mucus hypersecretion, and smooth muscle constriction, all of which narrow the airway lumen and impede airflow. Clinically, asthma presents with recurrent episodes of wheezing, shortness of breath, chest tightness, and coughing, symptoms that typically vary in intensity and...
Asthma-II: Pathophysiology and Classification01:26

Asthma-II: Pathophysiology and Classification

Asthma is a prevalent chronic respiratory condition marked by inflammation and hyperresponsiveness of the airways. Its pathophysiology involves complex interactions among inflammatory pathways, immune responses, and neural mechanisms.
Additionally, environmental and genetic factors play crucial roles in determining an individual's susceptibility to asthma and the severity of their condition.
Critical processes in asthma pathophysiology include:
Asthma: Pathogenesis and Management01:20

Asthma: Pathogenesis and Management

Asthma is a chronic pulmonary condition involving inflammation of the airways, hyper-reactivity, and reversible obstruction of the airways. This condition can significantly impact a person's quality of life, making breathing difficult and leading to distressing symptoms.
Asthma is classified as allergic and non-allergic. Allergens such as dust mites, pollen, and pet dander trigger allergic asthma, while factors like cold air, intense emotions, or exercise can induce non-allergic asthma.
Asthma-I: Introduction01:29

Asthma-I: Introduction

Asthma is a chronic respiratory ailment that requires careful management due to its varying symptoms and influencing factors. It is characterized by airway inflammation, bronchial hyperresponsiveness, and reversible airflow obstruction, leading to symptoms like wheezing, shortness of breath, chest tightness, and coughing. The symptom frequency and intensity may vary considerably over time. It is also linked to immune system responses to allergens and irritants, highlighting the complex...
Asthma III: Clinical Manifestations01:13

Asthma III: Clinical Manifestations

Asthma presents with a characteristic pattern of episodic respiratory symptoms that reflect underlying airway inflammation, bronchoconstriction, and mucus hypersecretion. Although severity varies among individuals, certain clinical manifestations are considered hallmarks of the disorder and often guide diagnosis and assessment.Respiratory SymptomsA persistent cough is one of the most common early features of asthma. It is frequently dry and tends to worsen at night or in the early morning,...
Asthma-III: Symptoms and Complications01:24

Asthma-III: Symptoms and Complications

Asthma, a common chronic respiratory condition, is classified considering the frequency and severity of symptoms alongside lung function impairment. Understanding this classification is essential for appropriate treatment and management. Here's a detailed look at the classification of asthma and its clinical features and complications:
Classification of Asthma