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Updated: Aug 16, 2026

Analyzing the Parkinson's Disease Mouse Model Induced by Adeno-associated Viral Vectors Encoding Human α-Synuclein
Published on: July 29, 2022
Neurodegenerative disorders: Parkinson's disease and Huntington's disease
S M Hague1, S Klaffke, O Bandmann
1Academic Neurology Unit, Division of Genomic Medicine, University of Sheffield, UK. o.bandmann@sheffield.ac.uk
Abstract:
Parkinson's disease and Huntington's disease are both model diseases. Parkinson's disease is the most common of several akinetic-rigid syndromes and Huntington's disease is only one of an ever growing number of trinucleotide repeat disorders. Molecular genetic studies and subsequent molecular biological studies have provided fascinating new insights into the pathogenesis of both disorders and there is now real hope for disease modifying treatment in the not too distant future for patients with Parkinson's disease or Huntington's disease.
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