Symptom panorama in upper secondary school students and symptoms related to iron deficiency. Screening with laboratory tests, questionnaire and interventional treatment with iron
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Updated: Aug 16, 2026

A Point-of-Care Method with Integrated Decision Support Tool to Estimate Anemia at Population Level
Published on: January 19, 2024
Jörgen Månsson1, Gunilla Johansson, Mona Wiklund
1Aranässkolan, Kungsbacka, Sweden. jorgen@huslakarna-kungsbacka.se
Objective:
To study symptom panorama in students, to identify undiagnosed iron deficiency, and to evaluate any changes in symptoms and laboratory test results after treatment with iron supplementation.
Design:
Descriptive and prospective, interventional study.
Setting:
Healthcare in upper secondary school.
Intervention:
Treatment with iron supplementation for a period of 3 months.
Subjects:
Students in the first grade of one upper secondary school.
Main Outcome Measures:
Frequency of iron deficiency related to symptoms measured by a questionnaire (30 questions) on symptoms related to quality of life and 9 questions about diet and exercise.
Results:
Iron deficiency was diagnosed in 12% of the students (two or more abnormal laboratory tests) and in 61% of the students one or more laboratory tests were abnormal. Symptoms of vertigo/ dizziness were significantly more common in students with iron deficiency. After iron supplementation there was a significant increase in s-ferritin levels and a decrease in s-transferrin levels, with an accompanying significant reduction of the symptom scores of vertigo/dizziness, irritability, depressive symptoms, and indisposition.
Conclusions:
Symptoms of vertigo/dizziness were significantly more common in students with iron deficiency. Iron supplementation reduced the symptoms of vertigo/dizziness, irritability, depressive symptoms, and indisposition.
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