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[Clinical study on effect of quyu xiaoban capsule on regression of atherosclerosis]
Yun-fang Liu1, Yu-xia Zhao, Hui-ming Yu
1Institute of Diagnostics, Medical College, Shandong University, Jinan 250012. liuyf@sdu.edu.cn
Objective:
To study the effect of Quyu Xiaoban capsule (QXC) on regression and stabilization of atherosclerotic plaque with high-frequency ultrasound technique.
Methods:
Eighty patients with atherosclerosis (AS) were randomly divided into the treated group and the control group, level of blood lipids was measured, and intima-media thickness (IMT) and corrected value of image average echo intensity (AIIc%) were determined by ultrasound technique at the beginning of experiment and after being treated for six months.
Results:
The levels of total cholesterol (TC) and low density lipoprotein cholesterol (LDL-C) were significantly decreased in the treated group after treatment (68.12 +/- 5.54 vs 61.43 +/- 5.37, P<0.05). The AIIc% of fatty atherosclerotic plaque was significantly increased after treatment (68.12 +/- 5.54 vs 61.43 +/- 5.37), and the change rate of AIIc% in the treated group was significantly different to that in the control group (10.9 +/- 5.1% vs 2.5 +/- 5.5%, P < 0.05).
Conclusion:
QXC can significantly lower the blood lipids level, delay the progress and enhance the stability of atherosclerotic plaque.