Related Experiment Video
Updated: Aug 16, 2026

Implantation of Total Artificial Heart in Congenital Heart Disease
Published on: July 18, 2014
Fatal cardiac tamponade in a patient with Kawasaki disease
1Department of Internal Medicine, Baskent University Faculty of Medicine, Adana Teaching and Medical Research Center, Adana, Turkey.
Insights
This case study details a rare, fatal outcome of Kawasaki disease (KD) in an 18-year-old man. Despite aggressive treatment, polyserositis and cardiac tamponade led to a fatal conclusion, highlighting severe KD complications.
Area of Science:
- Pediatric Cardiology
- Rheumatology
- Immunology
Background:
- Kawasaki disease (KD) typically resolves but can cause severe cardiac issues.
- Cardiac complications, including coronary artery aneurysms, are a significant concern in KD patients.
Observation:
- An 18-year-old male presented with rapidly progressive and fatal Kawasaki disease.
- The patient developed polyserositis syndrome and cardiac tamponade during the convalescent phase.
Findings:
- Standard treatments, including high-dose corticosteroids and intravenous immunoglobulin-G, were ineffective.
- Despite supportive care and pericardiocentesis for cardiac tamponade, the patient experienced a fatal outcome.
Implications:
- This case underscores the potential for severe, atypical presentations of KD in older individuals.
- It highlights the critical need for vigilance regarding cardiac complications, even in the later stages of Kawasaki disease.
Abstract:
Kawasaki disease (KD) is usually a self-limiting condition, but cardiac complications are not uncommon and can lead to significant morbidity and mortality. This article describes the case of an 18-year-old man with rapidly progressive and ultimately fatal KD. Polyserositis syndrome and cardiac tamponade developed during a convalescent phase of the illness. Treatment with high-dose corticosteroid and intravenous immunoglobulin-G therapy was unsuccessful. The patient continued to deteriorate despite supportive care. Severe cardiac tamponade developed, and percutaneous pericardiocentesis was performed, but the patient died hours later. This is the second reported case of KD featuring a polyserositis syndrome and impending cardiac tamponade, and the first with fatal outcome.
Related Concept Videos
Pericarditis IV: Nursing Management
Rheumatic Heart Disease IV: Nursing Management
Cardiomyopathy III: Hypertrophic Cardiomyopathy
Rheumatic Heart Disease I: Introduction
Imbalances in Cardiac Output
CHF can occur due to the failure of either side of the heart. Left-side failure leads to pulmonary congestion—the right side continues to send blood...
Aortic Regurgitation IV: Nursing Management