Cardiogenic embolism producing crescendo transient ischemic attacks
Patrick J Geraghty1, Jack Oak, Eric T Choi
1Department of Surgery, Section of Vascular Surgery, Washington University School of Medicine, 660 S. Euclid Avenue, Campus Box 8109, St. Louis, MO, 63110-1094, USA. geraghtyp@msnotes.wustl.edu
Insights
Atherosclerotic plaques at the carotid bifurcation can cause repetitive transient ischemic attacks. This case highlights how a cardiogenic embolus led to stroke symptoms, with full recovery after carotid surgery.
Area of Science:
- Neurology
- Vascular Surgery
- Cardiology
Background:
- Symptomatic carotid bifurcation atherosclerotic plaques often cause lateralizing, repetitive transient ischemic attacks (TIAs).
- Understanding the precise mechanisms of embolic events is crucial for effective stroke prevention and management.
Observation:
- A patient presented with crescendo episodes of expressive aphasia and mild right upper extremity weakness.
- These symptoms were attributed to a cardiogenic embolus lodging at the left carotid bifurcation.
Findings:
- Emergent carotid embolectomy and endarterectomy resulted in complete neurological recovery.
- The laminar flow within the internal carotid artery may localize embolic events to specific cerebral vasculature regions.
Implications:
- This case underscores the importance of considering embolic sources in TIAs, even with apparent carotid artery disease.
- Endoluminal techniques play a significant role in diagnosing and managing carotid bifurcation lesions causing embolic stroke.
Abstract:
Lateralizing, repetitive transient ischemic attacks are characteristic of symptomatic carotid bifurcation atherosclerotic plaques. We report a case in which a cardiogenic embolus, after lodging at the left carotid bifurcation, produced crescendo episodes of expressive aphasia and mild right upper extremity weakness. Complete neurological recovery was achieved following emergent carotid embolectomy and endarterectomy. This case demonstrates that the laminar nature of internal carotid blood flow may result in the localization of embolic events to a single region of the cerebral vasculature, regardless of the source lesion in the carotid artery. The role of endoluminal techniques in the diagnosis and management of such lesions is discussed.
Related Concept Videos
Transient Ischemic Attack l: Introduction
Acute Coronary Syndrome I: Introduction
Introduction Cardiac Emergencies
Ischemic Stroke l: Introduction
Acute Coronary Syndrome II: Pathophysiology and Clinical Manifestations
Coronary Artery Disease III: Clinical Manifestations

