Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Pyramidal tract imaging in multiple-system atrophy.

Nicole Limberg1, Susanne Jeavons, Thomas Robertson

  • 1Department of Neurology, Princess Alexandra Hospital, Brisbane, Australia.

Movement Disorders : Official Journal of the Movement Disorder Society
|July 20, 2005
PubMed
Summary

A novel T2 FLAIR hyperintensity finding in the pyramidal tracts was observed. This radiological sign aids in distinguishing multiple-system atrophy from Parkinson's disease.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Reconstructive Pelvic Anatomy classification system : a valid and reliable classification system for pelvic reconstruction.

Bone & joint open·2026
Same author

Development and validation of a real-time polymerase chain reaction for the detection of Haycocknema perplexum.

Pathology·2026
Same author

A modified Delphi consensus on tenosynovial giant cell tumour and giant cell tumour of bone : a report from the Birmingham Orthopaedic Oncology Meeting (BOOM).

The bone & joint journal·2026
Same author

Synaptosomes isolated from cryopreserved MND motor cortex reveal altered calcium handling and reduced complex IV-linked respiration.

Frontiers in synaptic neuroscience·2026
Same author

Complications of PI to PIII hemipelvic resections for intermediate and malignant tumours : a systematic review and meta-analysis.

Bone & joint open·2026
Same author

Robotic-assisted surgery and functional alignment in total knee arthroplasty: the RASKAL registry-nested 2 × 2 factorial randomized trial.

The bone & joint journal·2026

Area of Science:

  • Neurology
  • Radiology
  • Neuroimaging

Background:

  • Idiopathic Parkinson's disease and multiple-system atrophy (MSA) are neurodegenerative disorders that can present with overlapping clinical symptoms.
  • Accurate differentiation between these conditions is crucial for appropriate patient management and prognosis.

Observation:

  • A case study describes a patient initially suspected of having idiopathic Parkinson's disease based on clinical presentation.
  • However, subsequent histological examination confirmed the diagnosis of multiple-system atrophy.

Findings:

  • A distinct radiological finding was identified: T2 FLAIR hyperintensities within the pyramidal tracts on magnetic resonance imaging.
  • This specific imaging pattern was noted in the patient diagnosed with multiple-system atrophy.

Related Experiment Videos

Implications:

  • The described T2 FLAIR hyperintensity in pyramidal tracts may serve as a novel imaging biomarker for multiple-system atrophy.
  • This finding could potentially improve the diagnostic accuracy of differentiating MSA from Parkinson's disease, especially in early or ambiguous cases.