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Related Experiment Videos

Hepatic arterial cannulation using the side holed catheter.

Masashi Watanabe1, Wataru Takita, Masaru Tsuchiya

  • 1Department of Gastrointestinal Surgery (Omori), Toho University School of Medicine, 6-11-1 Ota-ku, Tokyo, Japan. res18@med.toho-u.ac.jp

Journal of Surgical Oncology
|July 20, 2005
PubMed
Summary

A novel side-holed catheter simplifies long-term hepatic arterial infusion chemotherapy (HAIC) delivery. This anti-thrombotic catheter reduces complications like hepatic artery occlusion, improving patient treatment outcomes.

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Area of Science:

  • Interventional Radiology
  • Surgical Oncology
  • Vascular Access Devices

Background:

  • Hepatic arterial infusion chemotherapy (HAIC) is effective for hepatic metastatic tumors but faces long-term delivery challenges.
  • Complications often hinder sustained HAIC treatment, necessitating improved delivery methods.
  • A novel catheter-port system implantation via laparotomy is presented.

Purpose of the Study:

  • To introduce a new anti-thrombotic, tapering, side-holed catheter for HAIC.
  • To evaluate the feasibility and initial outcomes of implanting this novel catheter-port system.
  • To assess the potential of this method in mitigating HAIC-related complications.

Main Methods:

  • A tapered (5F to 3.3F) anti-thrombotic catheter with a side hole was designed.

Related Experiment Videos

  • The catheter was inserted via the gastroduodenal artery into the common hepatic artery, with the tip placed in the aorta or splenic artery.
  • The catheter-port system was implanted laparotomically in four patients during abdominal surgery.

    • Main Results:

    • Successful cannulation was achieved in all four patients.
    • Two patients completed HAIC without complications at 6 months.
    • Two patients continued HAIC treatment at 9 and 8 months post-implantation.

    Conclusions:

    • The novel tapering side-holed catheter facilitates catheter-port system implantation for HAIC.
    • This technique may simplify the procedure by avoiding complex selective coiling.
    • The method shows promise in reducing the incidence of hepatic artery occlusion during long-term HAIC.