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Updated: Aug 16, 2026

An In vitro Model to Study Immune Responses of Human Peripheral Blood Mononuclear Cells to Human Respiratory Syncytial Virus Infection
Published on: December 10, 2013
Thrombocytosis at an early stage of respiratory tract viral infection
Masaru Kubota1, Haruko Maeda, Jun Yoshimoto
1Department of Paediatrics, Kobe City General Hospital, Kobe, Japan. mkubota@kcgh.gr.jp
Aim:
To determine whether thrombocytosis, a platelet count of more than 500 x 10(9)/l, occurs at an early stage of respiratory tract viral infection.
Methods:
The medical records of 345 patients with respiratory syncytial virus (RSV), influenza, measles, adenovirus or human herpes virus 6 infections were retrospectively reviewed.
Results:
The mean platelet count was significantly higher in RSV patients than in patients with other respiratory infections. Among the 29 patients with thrombocytosis, 24 (82.8%) had RSV infection.
Conclusion:
When thrombocytosis is positive at an early stage of respiratory tract infection, RSV should be taken into account as a causative agent.
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