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CDK5 regulates cell-cell and cell-matrix adhesion in human keratinocytes

N Nakano1, A Nakao, K Ishidoh

  • 1Atopy (Allergy) Research Center, Juntendo University School of Medicine, Tokyo, Japan. nbnakano@med.juntendo.ac.jp

The British Journal of Dermatology
|July 21, 2005
PubMed
Summary

Cyclin-dependent kinase 5 (CDK5) and its activator p35 play roles in skin cell adhesion. Reduced CDK5/p35 expression in psoriasis may contribute to the disease, impacting cell-matrix interactions.

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