Related Experiment Video
Updated: Aug 16, 2026

A Comprehensive Pipeline to Assess the Efficiency of Human Erythropoiesis In Vitro and Ex Vivo
Published on: January 10, 2025
[New indications for erythropoietin in clinical practice]
C Fernández Lago1, J Batlle Fonrodona
1Servicio de Hematología y Hemoterapia, Complexo Hospitalario Universitario Juan Canalejo, La Coruña, Departamento de Medicina, Universidad de Santiago de Compostela, La Coruna, Spain. CFerLag@canalejo.org
Abstract:
The utilization of rHuEp changed definitively the treatment and the natural history of anemia in patients with chronic renal insufficiency (CRI), and now is modifying the treatment of anemia of other non-renal patients as anemia of premature, anemia in onco-hematological illnesses, anemia in human immunodeficiency virus (HIV) infection, and for reduction of allogenic blood transfusions in surgery. We analyze briefly the clinical indications of rHuEpo and the possible complications secondary to its use.
Related Concept Videos
Erythropoiesis
Erythropoiesis
Factors Affecting Erythropoiesis
Several factors influence the erythrocyte production rate, with tissue oxygen level being among the most critical. Intense exercise or high altitudes can cause tissue hypoxia, which triggers the kidneys to release more erythropoietin (EPO) into the bloodstream.
EPO then...
Role of Hematopoietic Growth Factors
Thrombopoietin (TPO), mainly released by the liver,...
Chronic Kidney Disease II: Clinical Manifestations
Treatment for Pulmonary Arterial Hypertension: Endothelin Receptor Antagonists
ETs are synthesized through a complex sequence of enzymatic steps, primarily involving an enzyme referred to as endothelin-converting enzyme (ECE). Of...
