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Published on: January 23, 2019
Catheter-related thrombosis in hematologic patients
Marco Moia1, Agostino Cortelezzi, Anna Falanga
1Angelo Bianchi Bonomi Hemophilia and Thrombosis Center and Department of Hematology, IRCCS Maggiore Hospital and University of Milan, Milan, Italy.
Central venous catheters (CVCs) are vital for cancer patients but risk thrombotic events and infections. This review examines CVC complications and prevention strategies specifically in oncohematologic patients, highlighting the need for further research.
Area of Science:
- Oncology
- Hematology
- Vascular Access Devices
Background:
- Central venous catheters (CVCs) are essential for administering treatments like chemotherapy and parenteral nutrition in cancer patients.
- Their use has increased, leading to a greater focus on associated complications, particularly in oncohematologic populations.
- Complications, including thrombotic events and bloodstream infections, are a significant concern, especially with prolonged CVC dwell times.
Purpose of the Study:
- To review the use and complications of central venous catheters (CVCs) in oncohematologic patients.
- To discuss current understanding and management strategies for CVC-related thrombotic events and infections in this patient group.
- To identify gaps in knowledge and areas requiring further research regarding CVC safety in oncohematologic care.
Main Methods:
- Literature review focusing on studies related to CVC use, complications, and management in oncohematologic patients.
- Analysis of data on the incidence, risk factors, and outcomes of CVC-related thrombotic events and bloodstream infections.
- Evaluation of proposed prevention and treatment strategies, including thromboprophylaxis.
Main Results:
- CVC-related complications, such as thrombosis and infections, are a significant concern in oncohematologic patients.
- The exact incidence of these complications is not fully established and may be influenced by CVC improvements.
- Limited data exists for oncohematologic patients compared to solid tumor patients, underscoring a need for more research.
Conclusions:
- Central venous catheters are indispensable in oncohematologic care but carry inherent risks.
- Effective prevention and management of CVC-related complications are crucial for patient safety.
- Further clinical trials are necessary to optimize thromboprophylaxis and other preventive strategies in this vulnerable population.
Related Concept Videos
Cardiac Catheterization I: Pre-Procedure Overview
Cardiac Catheterization II: Right Heart Catheterization
Cardiac Catheterization IV: Nursing Management
Venous Thrombosis I: Introduction
Venous Thrombosis III: Interprofessional Care
Venous Thrombosis IV: Nursing Management

