Restriction endonuclease (EcoR1) analysis of Brucella ovis DNA

Seven Brucella ovis isolates from diverse sources (including two used in the manufacture of a Br. ovis vaccine, four field strains and a reference strain from the National Culture Type Collection in London) were subjected to bacterial restriction endonuclease DNA analysis using the endonuclease EcoR1. No genetic differences were detected. It was concluded that strain variation is unlikely to be a problem in Br. ovis control schemes, whether these are based on vaccination or on the eradication of the disease using serological tests.