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Updated: Aug 16, 2026
12:11
Analysis of Chromosome Segregation, Histone Acetylation, and Spindle Morphology in Horse Oocytes
Published on: May 11, 2017
Multiple defects in an aborted bovine foetus associated with chromosomal trisomy
J W Coates1, C G Rousseaux, S M Schmutz
1Department of Veterinary Pathology, University of Saskatchewan, Saskatoon, Saskatchewan, S7N OWO.
New Zealand Veterinary Journal
|October 1, 1987
Summary
A trisomic bovine fetus with multiple birth defects was identified. This first-time report links trisomy 27 to bovine fetal anomalies, emphasizing chromosomal aberrations
Area of Science:
- Veterinary Genetics
- Reproductive Biology
- Developmental Biology
Background:
- Multisystemic anomalies in aborted bovine fetuses can stem from various causes.
- Chromosomal abnormalities are a known factor in developmental defects.
Purpose of the Study:
- To investigate the genetic basis of multisystemic anomalies in an aborted bovine fetus.
- To report the first case of trisomy 27 in a bovine fetus.
Main Methods:
- Karyotyping of fetal fibroblast cells from pericardial sac.
- Trypsin-banding and Giemsa staining for chromosome analysis.
Main Results:
- The aborted bovine fetus exhibited a heart defect, cleft palate, pulmonary hypoplasia, and kyphoscoliosis.
- Karyotyping revealed trisomy in fetal cells.
- Chromosome analysis indicated the extra chromosome was likely Chromosome 27.
Conclusions:
- This study reports the first instance of trisomy 27 in a bovine fetus.
- Chromosomal aberrations, specifically trisomy 27, are significant causes of multisystemic fetal anomalies in cattle.
- Highlights the importance of cytogenetic analysis in diagnosing fetal abnormalities.
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