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Neosporosis in a pup
M P Reichel1, R N Thornton, P L Morgan
1Central Animal Health Laboratory, Wallaceville, P.O. Box 40063, Upper Hutt, New Zealand. reichelm@mqm.govt.nz
New Zealand Veterinary Journal
|July 21, 2005
Summary
A boxer pup with hindleg rigidity was diagnosed with Neospora infection. Serological tests and post-mortem examinations confirmed Neospora antibodies, highlighting its diagnostic utility in canine cases.
Area of Science:
- Veterinary Parasitology
- Canine Infectious Diseases
Background:
- Neospora caninum is a significant cause of abortion and neurological disease in dogs.
- Early diagnosis and treatment are crucial for managing Neospora infections in puppies.
Purpose of the Study:
- To investigate a case of suspected Neospora infection in a young boxer pup presenting with neurological signs.
- To evaluate diagnostic methods for Neospora caninum in canine cases.
Main Methods:
- Serological testing using indirect fluorescent antibody test (IFAT) for Neospora antibodies.
- Histopathology, immunohistochemistry, and polymerase chain reaction (PCR) on tissue samples.
- Latex agglutination test for Toxoplasma gondii antibodies.
Main Results:
- The affected pup exhibited a high IFAT titre (1:51,200) for Neospora antibodies; Toxoplasma testing was negative.
- The dam and one littermate also had elevated Neospora IFAT titres, indicating familial exposure.
- Post-mortem analyses confirmed Neospora infection.
Conclusions:
- Serological testing (IFAT) is a valuable tool for diagnosing Neospora caninum in live dogs.
- Histopathology, immunohistochemistry, and PCR provide definitive post-mortem confirmation.
- This case contributes to understanding Neospora infection dynamics in New Zealand canine populations.