Related Experiment Video
Updated: Aug 16, 2026
A Battery of Motor Tests in a Neonatal Mouse Model of Cerebral Palsy
Published on: November 3, 2016
A lower motor neuron disease in newborn Romney lambs
P D Anderson1, K H Parton, M G Collett
1Institute of Veterinary Animal and Biomedical Sciences, Massey University, Private Bag 11222, Palmerston North, New Zealand.
Aim:
To determine the cause and nature of a disease in newborn New Zealand Romney lambs characterised by progressive weakness and premature death.
Methods:
Affected lambs were examined clinically, humanely killed and submitted to necropsy. Selected fonmalin-fixed tissues were examined histologically. Data on the parentage of the lambs were collected.
Results:
The principle lesions found were degeneration and loss of neurons in ventral horns of the spinal cord and brain stem and Wallerian degeneration of motor nerves and denervation atrophy of skeletal muscles fibres.
Conclusion:
The lesions are those of a lower motor neuron disease which appeared to have a genetic cause.
