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Simultaneous multiple intracranial and spinal meningiomas
J M Roda1, J A Bencosme, A Pérez-Higueras
1Unit of Neurosurgery, Clínica San Camilo, Madrid, Spain.
Neurochirurgia
|May 1, 1992
Summary
This case study details a rare instance of a 50-year-old woman diagnosed simultaneously with four meningiomas, two intracranial and two spinal. The absence of neurofibromatosis highlights the unusual nature of this multiple tumor presentation.
Area of Science:
- Neurology
- Neurosurgery
- Oncology
Background:
- Meningiomas are tumors arising from the meninges, the membranes surrounding the brain and spinal cord.
- Multiple meningiomas are uncommon, with specific genetic syndromes like neurofibromatosis being a known risk factor.
- Simultaneous diagnosis of multiple, distinct meningiomas across different neural compartments is exceptionally rare.
Observation:
- A 50-year-old female patient presented with incidentally diagnosed meningiomas.
- The patient had two intracranial meningiomas and two spinal meningiomas.
- No clinical or diagnostic signs of neurofibromatosis were present.
Findings:
- The simultaneous occurrence of four meningiomas (two cranial, two spinal) in a patient without neurofibromatosis is a highly unusual presentation.
- This case underscores the possibility of multiple meningiomas arising independently of known genetic predispositions.
- Diagnostic imaging confirmed the presence and location of all four lesions at the time of initial assessment.
Implications:
- This case expands the understanding of meningioma epidemiology and presentation.
- It suggests that non-syndromic, multiple meningiomas can occur and require thorough investigation.
- Further research into the etiology of sporadic multiple meningiomas may be warranted.