Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Volume-guaranteed pressure-support ventilation facing acute changes in ventilatory demand.

Samir Jaber1, Jean-Marc Delay, Stefan Matecki

  • 1Intensive Care Unit, Anesthesia and Critical Care Department B, Saint Eloi Teaching Hospital, 34000 Montpellier, France. s-jaber@chu-montpellier.fr

Intensive Care Medicine
|July 21, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Correction: Partition of respiratory mechanics in patients with acute respiratory distress syndrome and association with outcome: a multicentre clinical study.

Intensive care medicine·2023
Same author

Low-Flow Inflation Pressure-Time Curve to Identify Airway Opening Pressure in a Patient Receiving Venovenous Extracorporeal Membrane Oxygenation.

American journal of respiratory and critical care medicine·2023
Same author

Weaning from mechanical ventilation in intensive care units across 50 countries (WEAN SAFE): a multicentre, prospective, observational cohort study.

The Lancet. Respiratory medicine·2023
Same author

Expiratory Muscle Relaxation-Induced Ventilator Triggering: A New Dyssynchrony or an Established Physiological Phenomenon?

Chest·2022
Same author

Reverse Triggering during Controlled Ventilation: From Physiology to Clinical Management.

American journal of respiratory and critical care medicine·2022
Same author

A meso-scale model of clay matrix: the role of hydration transitions in geomechanical behavior.

Soft matter·2022

Volume Support Ventilation (VSV) may cause respiratory distress when ventilatory demand increases, unlike Pressure Support Ventilation (PSV). VSV decreases pressure support, potentially worsening patient outcomes.

Area of Science:

  • Mechanical Ventilation
  • Respiratory Physiology

Background:

  • Mechanical ventilation is crucial for critically ill patients.
  • Optimizing ventilator settings is essential for patient recovery and comfort.
  • Understanding patient-ventilator synchrony is key during weaning.

Purpose of the Study:

  • To compare Volume Support Ventilation (VSV) with Pressure Support Ventilation (PSV).
  • To evaluate patient behavior and ventilator response under increased ventilatory demand.
  • To assess the impact of added dead space on ventilatory support modes.

Main Methods:

  • A randomized cross-over study was conducted in an intensive care unit.
  • Ten patients weaning off mechanical ventilation were included.
  • Ventilatory demand was increased by adding dead space to the circuit during PSV and VSV.

Related Experiment Videos

Main Results:

  • Increased dead space raised minute ventilation and PaCO2 in both PSV and VSV.
  • Respiratory effort and work of breathing increased significantly more with VSV (2.5-4 times) than PSV.
  • VSV showed a significant decrease in delivered pressure support, unlike PSV, and led to respiratory distress in two patients.

Conclusions:

  • Increased ventilatory demand with VSV leads to decreased pressure support, contrary to the intended response.
  • PSV maintained consistent pressure support, demonstrating better adaptability.
  • VSV may pose a risk of respiratory distress in clinical scenarios with increased ventilatory demand.