Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Dendritic structures based on bis(hydroxymethyl)propionic acid as platforms for surface reactions.

Emma Ostmark1, Lubica Macakova, Tommaso Auletta

  • 1KTH Fibre and Polymer Technology and KTH Chemistry, Surface Chemistry, Royal Institute of Technology, SE-100 44 Stockholm, Sweden.

Langmuir : the ACS Journal of Surfaces and Colloids
|July 22, 2005
PubMed
Summary

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Exploring the Antibacterial Potential of Bis-MPA Dendrimers Bearing Cu(II) and Zn(II) Complexes.

Biomacromolecules·2026
Same author

PEGylated Heterofunctional Dendrimers Enable Multivalent Diclofenac Delivery for ROS-Driven Anticancer Activity.

ACS applied materials & interfaces·2026
Same author

Hydrolytically Stable Cationic Bis-MPA Dendrimers as Efficient Transfectants for Glioblastoma Cells and Primary Astrocytes.

Biomacromolecules·2025
Same author

Heterofunctional Cationic Polyester Dendrimers as Potent Nonviral Vectors for siRNA Delivery.

Pharmaceutics·2025
Same author

Triazine-Trione Thermosets with High Processability for Scaffold Applications in Bone Tissue Engineering.

Advanced healthcare materials·2025
Same author

Cellulose nanopaper with polymeric nanoparticle additives - what is the role of nanoparticle surface functionality?

Nanoscale·2025

Researchers explored self-assembled dendritic structures on gold surfaces. Deprotection of these structures creates reactive hydroxyl-terminated surfaces, offering versatile platforms for further functionalization.

Area of Science:

  • Materials Science
  • Surface Chemistry
  • Nanotechnology

Background:

  • Dendritic structures based on 2,2-bis(hydroxymethyl)propionic acid offer precise molecular architectures.
  • Self-assembly onto surfaces is a key strategy for creating functional materials.
  • Protecting groups are essential for controlling reactivity during synthesis and assembly.

Purpose of the Study:

  • To investigate the self-assembly of different generations of dendritic structures onto gold surfaces.
  • To explore the deprotection of acetonide groups to form hydroxyl-terminated dendrons.
  • To compare surface properties resulting from on-surface versus in-solution deprotection.

Main Methods:

  • Synthesis of disulfide-cored dendritic structures (generations 1-3) with acetonide protecting groups.

Related Experiment Videos

  • Self-assembly of dendrons onto gold surfaces.
  • Hydrolysis of acetonide protecting groups, both on the surface and in solution.
  • Characterization of the resulting surface-attached dendrons and their properties.

    • Main Results:

    • Successful self-assembly of dendritic structures from generation 1 to 3 onto gold surfaces.
    • Effective deprotection of acetonide groups to yield hydroxyl-terminated dendrons.
    • Demonstration that deprotection can be performed both on-surface and in-solution, creating reactive platforms.
    • Differences observed in layer properties depending on the deprotection method (on-surface vs. in-solution).

    Conclusions:

    • Self-assembled dendritic structures provide a versatile route to functionalized surfaces.
    • Hydroxyl-terminated dendrons can be generated via acetonide deprotection, enabling further surface modification.
    • The method of deprotection influences the final properties of the surface-attached layers.