Related Experiment Video
Updated: Aug 16, 2026
Creation of Colonic Anastomosis in Mice
Published on: January 17, 2019
[Effect of guided adhesions on ischemic colic anastomoses in rats]
Miki Mochizuki1, Feng Chui Wu, Cláudio Saddy Rodrigues Coy
1Serviço de Coloproctologia da Faculdade de Ciências Médicas da UNICAMP. gastromiki@yahoo.com
Purpose:
Evaluate the effect of conducted adhesions on the mechanical resistance of anastomoses performed in ischemic colon through the Bursting Strength Test and Breaking Strength Test.
Methods:
Forty rats were divided into two groups. Group 1 was composed of 20 rats in which the anastomoses were covered with P.V.C. (Polyvinyl Chloride) to prevent the occurrence of adhesions over the anastomotic line. Group 2 was composed of 20 rats in which anastomotic line was covered with epididimal fat besides P.V.C. to prevent formation of other adhesions.
Results:
The mean Bursting Strength of the anastomoses in the group without adhesion was 10 mmHg and this value was 55.2 mmHg in the group with adhesion (p < 0.05). The mean Breaking Strength of the anastomoses was 142.5 gf in the group without adhesion and 262 gf in the group with adhesion (p < 0.05).
Conclusion:
Based on those mechanical tests, adhesions were benefic to ischemic anastomoses, rising their intrinsic resistance both on Bursting and Breaking Strength.
