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Updated: Aug 16, 2026

Intraportal Transplantation of Pancreatic Islets in Mouse Model
Published on: May 5, 2018
[Pancreas transplantation in the management of diabetes]
A De Roover1, O Detry, C Coimbra
1Service de Chirurgie abdominale, endocrine et transplantation, Nutrition et Maladies métaboliques, CHU Sart Tilman, Liège.
Abstract:
Pancreas transplantation has now become an established option in the treatment of diabetic complications. It normalizes glucose metabolism, prevents, stabilizes and improves the evolution of diabetes-associated lesions. Improvements in surgical procedure and in immunosuppression have better defined its indications. Combined kidney-pancreas transplantation appears today as the best treatment for the diabetic patient with end stage renal disease. Isolated pancreas transplantation is reserved to non-uremic patients with severe diabetic complications or with hyperlabile glycaemic control and severe impairment of quality of life.
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