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Idiopathic multicentric osteolysis: a case report and literature review

Rishi Singhal1, Javed Salim, Paul Walker

  • 1Department of Orthopaedics, North Lincolnshire and Goole Hospitals NHS Trust, Cliff Gardens, Scunthorpe DN21 7BH, United Kingdom. singhal_rishi@rediffmail.com

Acta Orthopaedica Belgica
|July 23, 2005
PubMed
Abstract

No abstract available in PubMed .

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Osteoclasts in Bone Remodeling01:31

Osteoclasts in Bone Remodeling

Osteoclasts are cells responsible for bone resorption and remodeling. They originate from hematopoietic progenitor cells present in the bone marrow. Numerous progenitor cells fuse to form multinucleated cells, each with 10-20 nuclei. A single osteoclast has a diameter of 150 to 200 µM. These cells have ruffled borders that break down the underlying bone tissue and release minerals such as calcium into the blood in bone resorption. Osteoclasts cling to bones with their ruffled edges during bone...