Behavioral manifestations associated with multiple sclerosis

M E Mahler1

  • 1Neurobehavior Program, Brentwood Division, West Los Angeles Department of Veterans Affairs Medical Center, California.

Insights

Multiple Sclerosis (MS) significantly impacts cognition and emotion, affecting intellect, memory, and executive functions. Management requires a multimodal approach including neurologic care, rehabilitation, and therapy.

Area of Science:

  • Neurology
  • Neuropsychology

Background:

  • Multiple Sclerosis (MS) is a chronic neurological disease.
  • Behavioral changes, including cognitive and emotional disturbances, are common in MS patients.

Purpose of the Study:

  • To summarize the range of behavioral manifestations in Multiple Sclerosis.
  • To highlight the impact of these changes on daily living and management strategies.

Main Methods:

  • Literature review of studies on cognitive and emotional changes in MS.
  • Analysis of reported prevalence and severity of impairments.

Main Results:

  • Cognitive impairments affect intellect (50%) and executive functions in MS patients.
  • Memory retrieval, concept formation, and emotional control disturbances are prevalent.
  • Depression is frequent, with occasional euphoria; psychosis is rare but bipolar disorder is more common.

Conclusions:

  • Behavioral disturbances are integral to Multiple Sclerosis, impacting quality of life.
  • Comprehensive management integrating neurologic care, cognitive rehabilitation, counseling, and pharmacotherapy is essential.

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