Related Experiment Video
Updated: Aug 16, 2026

Fluorescence-Activated Cell Sorting for the Isolation of Scleractinian Cell Populations
Published on: May 31, 2020
Cytotoxic diterpenoids from the soft coral Sinularia microclavata
Cui-Xian Zhang1, Su-Jun Yan, Guang-Wen Zhang
1School of Chemistry and Chemical Engineering, Sun Yat-sen University, Guangzhou, 510275, People's Republic of China.
Abstract:
The soft coral Sinularia microclavata collected from the bay of Sanya, Hainan Island, China, yielded a new diterpenoid, microclavatin (1), and a known cembranolide, capillolide (2). The structure of compound 1 was determined on the basis of spectroscopic methods and X-ray single-crystal diffraction analysis. Microclavatin (1) showed cytotoxic activities against tumor cell lines KB and MCF with IC50 values of 5.0 and 20.0 microg/mL, respectively, and capillolide (2) showed potent cytotoxic activity against tumor cell lines (A-549) with an IC50 value of 0.5 microg/mL.
Related Concept Videos
Drugs that Destabilize Microtubules
Diversity of Protists II
Diphtheria
Red Algae
Antifungal Agents
Gene Regulation in Microbial Communities: Quorum Sensing

