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Updated: Aug 16, 2026

Biological Compatibility Profile on Biomaterials for Bone Regeneration
Published on: November 16, 2018
Use of bone graft substitutes and bioactive materials in treatment of distal radius fractures
Brian J Hartigan1, Mark S Cohen
1Department of Orthopaedic Surgery, Northwestern University, Feinberg School of Medicine, Chicago, IL, USA; Northwestern Center for Orthopedics, 676 North St. Clair, Suite 450, Chicago, IL 60611, USA. bjhartigan@hotmail.com
Abstract:
Although autogenous bone graft has been shown to be useful in the treatment of distal radius fractures, the role of bone graft substitutes and the optimal replacement material remains unclear. Several products are commercially available, each with differing osteoconductive, osteoinductive, and structural properties. Indications and choice of graft substitute should be based on the needs of the individual case with regard to need for structural support, gap filling, or bone healing stimulation. Further comparative research will help clarify the indications and most appropriate material for a given fracture and clinical situation.
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