Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Visual deprivation effects on human motor cortex excitability.

Fidias E Leon-Sarmiento1, William Bara-Jimenez, Eric M Wassermann

  • 1Brain Stimulation Unit, National Institute of Neurological Disorders and Stroke, National Institutes of Health, Bethesda, MD, USA. feleoness@yahoo.com

Neuroscience Letters
|July 26, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

The Effects of Craniofacial Muscle Contractions on the Formerly Vagus Nerve Somatosensory Evoked Potentials.

Cureus·2025
Same author

Neuropsychiatric and behavioral symptom clusters in frontotemporal dementia.

Journal of Alzheimer's disease reports·2025
Same author

Combined effects of pharmacological interventions and intermittent theta-burst stimulation on motor sequence learning.

bioRxiv : the preprint server for biology·2024
Same author

Demographic and Symptom Correlates of Initial Idiopathic Psychiatric Diagnosis in Frontotemporal Dementia.

Journal of geriatric psychiatry and neurology·2022
Same author

Effective connectivity underlying neural and behavioral components of prism adaptation.

Frontiers in psychology·2022
Same author

Elevations in Tumor Necrosis Factor Alpha and Interleukin 6 From Neuronal-Derived Extracellular Vesicles in Repeated Low-Level Blast Exposed Personnel.

Frontiers in neurology·2022

Temporary visual deprivation enhances motor cortex excitability and reduces inhibition in healthy adults. This visual deafferentation may offer novel insights into brain plasticity and TMS study confounds.

Area of Science:

  • Neuroscience
  • Motor Control
  • Brain Plasticity

Background:

  • Transcranial magnetic stimulation (TMS) is a tool to probe motor cortex excitability.
  • Visual input can influence motor system function.
  • Understanding factors affecting motor cortex excitability is crucial for neuroscience research.

Purpose of the Study:

  • To investigate the effects of temporary visual deafferentation on human motor cortex excitability.
  • To explore whether visual deprivation alters intracortical inhibition.
  • To assess potential confounds in TMS studies due to visual conditions.

Main Methods:

  • Single and paired-pulse transcranial magnetic stimulation (TMS) applied to the motor cortex.
  • 12 healthy volunteers participated.

Related Experiment Videos

  • Conditions included eyes-open, eyes-closed, and 30 minutes of blindfolding.

    • Main Results:

    • Significantly larger motor-evoked potentials observed during blindfolding compared to eyes-open.
    • Reduced intracortical inhibition noted during blindfolding.
    • Visual deafferentation demonstrably alters resting motor cortex excitability.

    Conclusions:

    • Temporary visual deafferentation enhances human motor cortex excitability.
    • Visual deprivation may be a novel method to promote brain plasticity.
    • Findings highlight a potential confound in TMS studies of the motor cortex.