Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Electronic transport in DNA.

Daphne Klotsa1, Rudolf A Römer, Matthew S Turner

  • 1Physics Department and Centre for Scientific Computing, University of Warwick, Coventry, United Kingdom.

Biophysical Journal
|July 26, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Quantum Storage with Flat Bands.

Physical review letters·2026
Same author

The theory of epidemics with altruism.

Proceedings of the National Academy of Sciences of the United States of America·2026
Same author

Self-organized social distancing during epidemics when the force of infection depends on susceptible and infectious behavior.

Mathematical biosciences and engineering : MBE·2026
Same author

Large-angle convergent-beam electron diffraction patterns via conditional generative adversarial networks.

Ultramicroscopy·2025
Same author

Binary mixtures of active Brownian particles with distinct nonzero activities.

Soft matter·2025
Same author

Charge distribution and helicity tune the binding of septin's amphipathic helix domain to membranes.

Biophysical journal·2025
Same journal

Enhanced-Sampling Simulations Reveal Distinct Intermediates in SARS-CoV-2 FSE Pseudoknot Interconversion.

Biophysical journal·2026
Same journal

Structure-based simulations of the full Flock House virus capsid reveal pathways and energetics of an infection-critical peptide externalization event.

Biophysical journal·2026
Same journal

Quantifying the Peripheral Surface Information Entropy from Conformational Ensembles of Globular Protein-Peptide Complexes.

Biophysical journal·2026
Same journal

Anisotropic unbinding and location-dependent hovering of a kinesin motor head over microtubule.

Biophysical journal·2026
Same journal

Kinesin-5/Cut7 C-terminal tail phosphorylation influence on motor regulation through multi-scale molecular modeling.

Biophysical journal·2026
Same journal

Dynamic conformations of fluorophores on self-labeling protein tags.

Biophysical journal·2026
See all related articles

Electron transport in DNA is limited, with short movement distances observed in random and lambda-DNA sequences. Disorder can enhance electron movement in DNA, suggesting potential biological relevance for charge transfer.

Area of Science:

  • Molecular Biophysics
  • Computational Biology
  • Genetics

Background:

  • Understanding DNA's electronic properties is crucial for comprehending its biological functions.
  • Charge transfer within DNA is influenced by its sequence and structural environment.

Purpose of the Study:

  • To investigate the electronic properties and charge transfer capabilities of specific DNA sequences.
  • To analyze the impact of various types of disorder on DNA's electron transport.

Main Methods:

  • Utilized a tight-binding model for electronic property calculations.
  • Performed simulations on four distinct DNA sequences: poly(dG)-poly(dC), telomeric DNA, random ATGC DNA, and lambda DNA.
  • Introduced random potentials and binary backbone disorder to model environmental effects.

Related Experiment Videos

Main Results:

  • Calculated localization lengths, indicating the extent of electron motion.
  • Found limited electron motion (few dozen basepairs) in random and lambda-DNA.
  • Observed a novel enhancement of localization lengths at specific energies with increased binary backbone disorder.

Conclusions:

  • DNA's charge transfer properties are sequence-dependent and affected by disorder.
  • The observed localization lengths suggest constraints on long-range electron transport in certain DNA structures.
  • The findings may have implications for understanding sequence-dependent biological processes involving DNA charge transfer.