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Published on: June 4, 2012
[Eikenella corrodens infective endocarditis]
Juliano Novaes Cardoso1, Marcelo Eidi Ochiai, Múcio T Oliveira
1Instituto do Coração do Hospital das Clínicas, FMUSP, São Paulo, SP. julianonc@hotmail.com
Insights
The HACEK group (Haemophilus spp, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella kingae) cause a small percentage of endocarditis cases. This report details a rare case of Eikenella corrodens endocarditis.
Area of Science:
- Infectious Diseases
- Microbiology
Background:
- The HACEK group comprises fastidious Gram-negative bacteria commonly found in the upper respiratory tract.
- These microorganisms are associated with a specific subset of infective endocarditis cases, representing approximately 3% of all instances.
- Diagnosis can be challenging due to their slow growth and fastidious nature, often requiring prolonged incubation.
Observation:
- Endocarditis caused by HACEK organisms typically presents with insidious clinical symptoms.
- Microbiological cultures may yield negative results, complicating the diagnostic process.
- Eikenella corrodens, a member of the HACEK group, was first identified as an endocarditis agent in 1972.
Findings:
- This case report describes Eikenella corrodens infective endocarditis in a female patient with a native valve.
- Eikenella corrodens remains a rare etiological agent for infective endocarditis.
Implications:
- Understanding the unique characteristics of HACEK-related endocarditis is crucial for timely diagnosis and effective treatment.
- This case highlights the importance of considering rare pathogens in the differential diagnosis of endocarditis, even with negative initial cultures.
- Further research into the optimal diagnostic and therapeutic strategies for HACEK endocarditis is warranted.
Abstract:
The HACEK microorganisms (Haemophilus spp, Actinobacillus actinomycetemcomitans, Cardiobacterium hominis, Eikenella corrodens, and Kingella kingae) account for 3% of the cases of endocarditis. They have the following similar clinical and microbiological properties: are Gram-negative bacilli, more easily isolated in aerobic media; their cultures require prolonged incubation time for growing (mean, 3.3 days); and may be considered part of normal flora of upper respiratory tract and oropharynx. The following characteristics have been identified in endocarditis caused by the HACEK microorganisms: insidious clinical findings; difficult diagnosis due to the fastidious nature of the microorganisms; and negative cultures. The Eikenella corrodens endocarditis was first described in 1972. That microorganism continues to be a rare etiological agent. We report the case of a female patient with native valve, who had Eikenella corrodens infective endocarditis.
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