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Cholesterol pericarditis--relapsing pericardial effusion in a patient with rheumatoid arthritis
Luís Raposo1, Maria João Andrade, Jorge Ferreira
1Serviço de Cardiologia, Hospital de Santa Cruz, Carnaxide, Portgal. lforl@clix.pt
Insights
Cholesterol pericarditis, a rare condition causing large effusions, can be linked to rheumatoid arthritis. Surgical treatment proved effective for a patient with rheumatoid arthritis presenting with heart failure due to pericardial effusion.
Area of Science:
- Cardiology
- Rheumatology
Background:
- Cholesterol pericarditis is an uncommon pericardial disease characterized by large, cholesterol-rich effusions.
- Pathophysiology is largely unknown, often idiopathic but associated with systemic diseases like rheumatoid arthritis.
Observation:
- A 61-year-old female patient with rheumatoid arthritis presented with heart failure.
- The patient had a large pericardial effusion, a known complication of cholesterol pericarditis.
Findings:
- The patient's condition was successfully treated with a surgical approach.
- Surgical intervention is indicated in a subset of cholesterol pericarditis cases, particularly when linked to rheumatoid arthritis.
Implications:
- Highlights the importance of considering cholesterol pericarditis in rheumatoid arthritis patients with pericardial effusions.
- Suggests surgery as a viable treatment option for complex cases of rheumatoid arthritis-associated cholesterol pericarditis.
Abstract:
Cholesterol pericarditis is an uncommon form of pericardial disease, of unknown pathophysiology, that is characterized by chronic relapsing, usually large, pericardial effusions that are distinctive due to a high level of cholesterol. Usually it is idiopathic, but it can be associated with various systemic diseases such as hypothyroidism, rheumatoid arthritis and tuberculosis, among others. Its clinical course is usually indolent and complications such as cardiac tamponade and chronic constrictive pericarditis are relatively rare. However, the need for surgery for complete treatment has been reported in at least 10 % of cases. When rheumatoid arthritis is the underlying cause, this outcome is more frequent among those with an acute episode of pericarditis during the course of the disease. We report the case of a 61-year-old female rheumatoid arthritis patient, who presented with heart failure due to a large pericardial effusion and was successfully treated by a surgical approach.
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