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Related Experiment Videos

Physical activity and multiple sclerosis: a meta-analysis.

Robert W Motl1, Edward McAuley, Erin M Snook

  • 1Department of Kinesiology, University of Illinois, 332 Freer Hall, Urbana, IL 61801, USA. robmotl@uiuc.edu

Multiple Sclerosis (Houndmills, Basingstoke, England)
|July 27, 2005
PubMed
Summary
This summary is machine-generated.

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Individuals with multiple sclerosis (MS) are less physically active than healthy people. This meta-analysis synthesized studies comparing physical activity levels in MS patients to other groups.

Area of Science:

  • Neurology
  • Rehabilitation Science
  • Exercise Physiology

Background:

  • Multiple sclerosis (MS) is a chronic neurological disease affecting physical function.
  • Physical activity is crucial for managing MS symptoms and maintaining quality of life.
  • Understanding physical activity levels in MS populations is essential for targeted interventions.

Purpose of the Study:

  • To quantitatively synthesize the difference in physical activity between individuals with MS and control groups (nondiseased and diseased).
  • To identify factors (moderators) that explain variations in physical activity differences.
  • To provide a comprehensive overview of physical activity in MS.

Main Methods:

  • A meta-analytic procedure was employed for quantitative synthesis.

Related Experiment Videos

  • Searches were conducted in MEDLINE, PsycINFO, and Current Contents Plus using keywords related to physical activity and MS.
  • Manual searches of bibliographies and author contact were used to identify additional relevant studies.

    • Main Results:

    • Fifty-three effects from 13 studies involving 2360 MS participants were analyzed.
    • A weighted mean effect size (ES) of -0.60 indicated lower physical activity in MS populations.
    • Physical activity differences were larger when using objective measures, comparing to nondiseased groups, and in primary progressive MS versus relapsing-remitting MS.

    Conclusions:

    • Individuals with MS exhibit lower physical activity levels compared to nondiseased populations.
    • The physical activity levels of individuals with MS are comparable to other diseased populations.
    • Objective measurement tools and specific MS subtypes influence the observed differences in physical activity.