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Published on: January 26, 2018
Linum mucronatum: organ to organ lignan variations
Abdolali Mohagheghzadeh1, Azra Gholami, Mohammad Soltani
1Department of Pharmacognosy, Faculty of Pharmacy, Shiraz University of Medical Sciences and Health Services, Shiraz, IR Iran. Mohaghegh@sums.ac.ir
Abstract:
The percentage of podophyllotoxin (PTOX) and its congener lignans were measured by HPLC in Linum mucronatum ssp. mucronatum (Linaceae) fresh plant organs. The highest amounts of PTOX (0.595 +/- 0.060% g/g dry wt) and 6-methoxypodophyllotoxin (MPTOX) (1.491 +/- 0.125% g/g dry wt) were found in the plant sexual organs. Whereas, the highest levels of beta-peltatin, 5'-demethoxy-MPTOX and yatein were found in not developed buds, petals and sepals, respectively.
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