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Intracardiac thrombus in Behçet's disease: two case reports
Sonia Hammami1, Silvia Mahjoub, Khaldoun Ben-Hamda
1Department of Internal Medicine, F Bourguiba University Hospital, Monastir, Tunisia. Sonia.Hammami@fmm.rnu.tn
Thrombosis Journal
|July 27, 2005
Summary
Intracardiac thrombus is a rare Behçet's disease complication. Medical management with immunosuppressants and anticoagulation led to complete thrombus dissolution and clinical improvement in two patients.
Area of Science:
- Cardiology
- Rheumatology
- Vascular Medicine
Background:
- Behçet's disease is a rare systemic vasculitis.
- Intracardiac thrombus formation is an exceptionally uncommon manifestation.
- This study presents two unique cases of intracardiac thrombus in Behçet's disease.
Purpose of the Study:
- To report and characterize rare cases of intracardiac thrombus in Behçet's disease.
- To evaluate the efficacy of medical management for intracardiac thrombus in this context.
Main Methods:
- Case report of two patients diagnosed with Behçet's disease and intracardiac thrombus.
- Diagnostic tools included helical CT and transoesophageal echocardiography.
- Treatment involved immunosuppressive and anticoagulation therapy.
Main Results:
- Two male patients, aged 20 and 29, presented with symptoms including dyspnea, cough, hemoptysis, fever, and chest pain.
- Diagnoses included right heart thrombus with pulmonary artery aneurysm and thromboembolism, and right atrial thrombosis with pulmonary embolism and hyperhomocysteinemia.
- Medical management resulted in complete thrombus dissolution and significant clinical improvement in both cases.
Conclusions:
- Intracardiac thrombus is a rare but significant complication of Behçet's disease.
- Medical management, including immunosuppression and anticoagulation, is an effective first-line treatment approach.