Jove
Visualize
Contact Us
JoVE
x logofacebook logolinkedin logoyoutube logo
ABOUT JoVE
OverviewLeadershipBlogJoVE Help Center
AUTHORS
Publishing ProcessEditorial BoardScope & PoliciesPeer ReviewFAQSubmit
LIBRARIANS
TestimonialsSubscriptionsAccessResourcesLibrary Advisory BoardFAQ
RESEARCH
JoVE JournalMethods CollectionsJoVE Encyclopedia of ExperimentsArchive
EDUCATION
JoVE CoreJoVE BusinessJoVE Science EducationJoVE Lab ManualFaculty Resource CenterFaculty Site
Terms & Conditions of Use
Privacy Policy
Policies

Related Experiment Videos

Postictal diffusion tensor imaging.

Beate Diehl1, Mark R Symms, Philip A Boulby

  • 1NSE MRI Unit, Department of Clinical and Experimental Epilepsy, Institute of Neurology, University College, London, UK.

Epilepsy Research
|July 27, 2005
PubMed
Summary
This summary is machine-generated.

Related Concept Videos

You might also read

Related Articles

Articles linked to this work by shared authors, journal, and citation graph.

Sort by
Same author

Postmortem MRI reveals distinct structural features in sudden unexpected death in epilepsy.

Epilepsia open·2026
Same author

The heartbeat evoked potential and the prediction of functional seizure semiology.

Brain communications·2026
Same author

Bilateral ictal eye closure in focal epileptic seizures: SEEG retrospective observational assessment from a tertiary epilepsy center.

Epileptic disorders : international epilepsy journal with videotape·2026
Same author

Dual mechanism of anti-seizure medications in controlling seizure activity.

Brain communications·2026
Same author

Association of Interictal Respiratory Variability and Severity of Postictal Hypoxemia After Generalized Convulsive Seizures.

Neurology·2026
Same author

Communication regarding sudden unexpected death in epilepsy to people with epilepsy and their caregivers: A scoping review from the ILAE Sudden Unexpected Death in Epilepsy Task Force.

Epilepsia·2026
Same journal

Access to inpatient video-EEG monitoring for patients with frequent seizure-related emergency visits.

Epilepsy research·2026
Same journal

Effect of the ketogenic diet on absence seizures in rats with genetic absence epilepsy.

Epilepsy research·2026
Same journal

Diagnostic accuracy of artificial intelligence models for seizure outcome prediction after epilepsy surgery: A systematic review and meta-analysis.

Epilepsy research·2026
Same journal

Quality assessment of persian epilepsy mobile applications: A systematic review using uMARS and DISCERN.

Epilepsy research·2026
Same journal

Effectiveness and safety of brivaracetam in patients with focal epilepsy: A systematic review and meta-analysis.

Epilepsy research·2026
Same journal

Small sharp spikes precede the development of epileptiform discharges in temporal lobe epilepsy.

Epilepsy research·2026
See all related articles

Postictal diffusion tensor imaging (DTI) reveals significant brain diffusivity changes in focal epilepsy patients, potentially indicating cellular swelling. These findings suggest DTI may aid in presurgical evaluations.

Area of Science:

  • Neuroimaging
  • Epileptology
  • Diffusion Tensor Imaging

Background:

  • Focal epilepsy presents diagnostic challenges, necessitating advanced imaging techniques.
  • Diffusion Tensor Imaging (DTI) offers insights into brain tissue microstructure.

Purpose of the Study:

  • To investigate postictal changes in brain diffusion properties using DTI in patients with focal epilepsy.
  • To compare diffusion metrics between postictal, interictal, and control states.

Main Methods:

  • DTI and statistical parametric mapping (SPM) were employed.
  • 18 patients with intractable focal epilepsy and 27 healthy controls were scanned.
  • Statistical analyses compared interictal, postictal, and control DTI data.

Main Results:

Related Experiment Videos

  • 72% of patients showed increased interictal mean diffusivity.
  • 50% exhibited focal postictal decreases in mean diffusivity, correlating with seizure foci in some cases.
  • No significant changes in fractional anisotropy were observed between postictal and interictal states.

Conclusions:

  • Postictal diffusivity decreases likely reflect cellular swelling at the seizure onset zone.
  • DTI reveals dynamic, focal postictal changes, but anisotropy measures are less sensitive.
  • Further research is needed to establish the role of postictal DTI in epilepsy presurgical evaluation.