Mechanistic insights into glaucoma provided by experimental genetics the cogan lecture

A Topographical Analysis of Visual Field Improvement in a Phase 2 Randomized Trial of Nicotinamide and Pyruvate for Open-Angle Glaucoma.

Investigative ophthalmology & visual science·2026

Single-cell characterization of anterior segment development in the mouse reveals the cell types, pathways, and signals driving formation of the trabecular meshwork and Schlemm's canal.

eLife·2026

Schlemm's Canal Development and Implications for Glaucoma Treatment.

Annual review of vision science·2026

Intraocular pressure induced blood retinal barrier compromise in mouse models and human glaucoma.

Nature communications·2026

Resident tissue macrophages maintain intraocular pressure homeostasis.

Immunity·2026

Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment.

eLife·2026

Gut Microbial Metabolite Indole-3-Acetic Acid Exerts Protective Effects by Regulating Orbital Fibroblast Fibrosis in Thyroid Eye Disease.

Investigative ophthalmology & visual science·2026

Aqueous Humor Proteomics Reveals the Molecular Basis for Differential Treatment Responses in nAMD and pmCNV.

Investigative ophthalmology & visual science·2026

Pathological P-Selectin Upregulation Promotes Retinal Ganglion Cell Degeneration Accompanied by T-Cell Recruitment in Glaucoma.

Investigative ophthalmology & visual science·2026

External Dynamic Visual Noise Matched to the Appearance of Visual Snow Fails to Reproduce Key Perceptual Properties of the Phenomenon.

Investigative ophthalmology & visual science·2026

Targeting RhoA/ROCK Signaling to Modulate Extracellular Matrix Remodeling in Corneal Endothelial Dystrophies.

Investigative ophthalmology & visual science·2026

LPA1-Induced EMT of Retinal Pigment Epithelial Cells Promotes Subretinal Fibrosis via USP1-Mediated Deubiquitination and Stabilization of ZEB1.

Investigative ophthalmology & visual science·2026

Clinical and Molecular Findings in Two Siblings with a Novel Homozygous DCAF17 Frameshift Variant and Review of the Literature: A Case Report.

Molecular syndromology·2026

Integrative methylome and transcriptome analysis reveals genotype and sequence context-specific responses to aluminum stress in rice.

Frontiers in plant science·2026

AdaBoost-based differential diagnosis of gouty arthritis and rheumatoid arthritis: model construction, temporal validation, and SHAP visualization.

Frontiers in medicine·2026

Refining genetic discoveries of group knockoffs via a feature-level filter.

Journal of the Royal Statistical Society. Series C, Applied statistics·2026

Spatial decoupling of plaque and circulating immune programs defines a robust gene signature in atherosclerosis: A multi-cohort integrative analysis.

Medicine·2026

Causal relationship between dietary habits and low hand grip strength: A Mendelian randomization study.

Medicine·2026

Related Experiment Videos

Mechanistic insights into glaucoma provided by experimental genetics the cogan lecture

Related Concept Videos

A Topographical Analysis of Visual Field Improvement in a Phase 2 Randomized Trial of Nicotinamide and Pyruvate for Open-Angle Glaucoma.

Single-cell characterization of anterior segment development in the mouse reveals the cell types, pathways, and signals driving formation of the trabecular meshwork and Schlemm's canal.

Schlemm's Canal Development and Implications for Glaucoma Treatment.

Intraocular pressure induced blood retinal barrier compromise in mouse models and human glaucoma.

Resident tissue macrophages maintain intraocular pressure homeostasis.

Single-cell profiling of trabecular meshwork identifies mitochondrial dysfunction in a glaucoma model that is protected by vitamin B3 treatment.

Gut Microbial Metabolite Indole-3-Acetic Acid Exerts Protective Effects by Regulating Orbital Fibroblast Fibrosis in Thyroid Eye Disease.

Aqueous Humor Proteomics Reveals the Molecular Basis for Differential Treatment Responses in nAMD and pmCNV.

Pathological P-Selectin Upregulation Promotes Retinal Ganglion Cell Degeneration Accompanied by T-Cell Recruitment in Glaucoma.

External Dynamic Visual Noise Matched to the Appearance of Visual Snow Fails to Reproduce Key Perceptual Properties of the Phenomenon.

Targeting RhoA/ROCK Signaling to Modulate Extracellular Matrix Remodeling in Corneal Endothelial Dystrophies.

LPA1-Induced EMT of Retinal Pigment Epithelial Cells Promotes Subretinal Fibrosis via USP1-Mediated Deubiquitination and Stabilization of ZEB1.

Clinical and Molecular Findings in Two Siblings with a Novel Homozygous DCAF17 Frameshift Variant and Review of the Literature: A Case Report.

Integrative methylome and transcriptome analysis reveals genotype and sequence context-specific responses to aluminum stress in rice.

AdaBoost-based differential diagnosis of gouty arthritis and rheumatoid arthritis: model construction, temporal validation, and SHAP visualization.

Refining genetic discoveries of group knockoffs via a feature-level filter.

Spatial decoupling of plaque and circulating immune programs defines a robust gene signature in atherosclerosis: A multi-cohort integrative analysis.

Causal relationship between dietary habits and low hand grip strength: A Mendelian randomization study.

Related Experiment Videos

Mechanistic insights into glaucoma provided by experimental genetics the cogan lecture

Related Concept Videos

Related Articles