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Diagnosis of ectopic gastric mucosa using 99Tcm-pertechnetate: spectrum of scintigraphic findings
R Kumar1, M Tripathi, N Chandrashekar
1Department of Nuclear Medicine, All India Institute of Medical Sciences, New Delhi, India.
Insights
Technetium Tc-99m pertechnetate scintigraphy reveals diverse patterns of ectopic gastric mucosa in children. Delayed imaging is crucial for detecting intrathoracic lesions, aiding diagnosis.
Area of Science:
- Nuclear Medicine
- Pediatric Radiology
- Gastroenterology
Background:
- Ectopic gastric mucosa can occur in various locations, presenting diagnostic challenges.
- Scintigraphy using Technetium Tc-99m pertechnetate is a key imaging modality for detecting functioning ectopic gastric mucosa.
Purpose of the Study:
- To illustrate the spectrum of scintigraphic findings in children with ectopic gastric mucosa.
- To emphasize the utility of delayed imaging in specific ectopic gastric mucosa locations.
Main Methods:
- Retrospective analysis of 11 pediatric patients undergoing Technetium Tc-99m pertechnetate scintigraphy.
- Evaluation of scintigraphic patterns based on the location of ectopic gastric mucosa (Meckel's diverticula, intestinal duplications, gastric duplications, intrathoracic duplication cysts).
Main Results:
- Functioning ectopic gastric mucosa was identified in Meckel's diverticula (3), small bowel duplications (4), gastric duplication (1), and intrathoracic foregut duplication cysts (3).
- Simultaneous visualization with the stomach occurred for Meckel's and gastric duplications.
- Intestinal duplications showed earlier or dynamic tracer visualization.
- Delayed images were essential for detecting ectopic gastric mucosa in intrathoracic duplication cysts.
Conclusions:
- Technetium Tc-99m pertechnetate scintigraphy demonstrates varied patterns of ectopic gastric mucosa.
- Delayed imaging is critical for diagnosing ectopic gastric mucosa in intrathoracic duplication cysts when initial images are inconclusive.
- Understanding these scintigraphic patterns aids in accurate diagnosis and management.
Abstract:
We highlight the spectrum of scintigraphic findings likely to be encountered in patients with ectopic gastric mucosa with illustrative cases for each such finding. 11 children (aged 4 months to 120 months, all males) underwent (99)Tc(m)-pertechnetate scintigraphic evaluation for ectopic gastric mucosa. Functioning ectopic gastric mucosa was detected in Meckel's diverticulae in three patients, in small bowel duplications in four, in a gastric duplication in one, and in intrathoracic foregut duplication cysts in three. Ectopic functioning gastric mucosa in Meckel's diverticulum, and gastric duplication is visualized simultaneously with the stomach while in intestinal duplications tracer activity can be visualized in the dynamic sequence and even before gastric tracer visualization. In the three patients with intrathoracic duplication cysts, the functioning ectopic gastric mucosa was evident only in the delayed (99)Tc(m)-pertechnetate images, much later than the visualization of stomach activity. Therefore, acquisition of delayed images are useful when the initial images are equivocal or negative in children with intrathoracic foregut duplication cysts. In addition, we suggest a hypothesis of a possible mechanism for the uptake of pertechnetate in ectopic gastric mucosa in some patients with intrathoracic forget duplication cysts. In conclusion, a variety of scintigraphic patterns may be found in patients with ectopic gastric mucosa undergoing (99)Tc(m)-pertechnetate scintigraphy depending upon the location and size of the ectopic tissue.
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