Related Experiment Video
Updated: Aug 12, 2026

Novel Diagnostics in Revision Arthroplasty: Implant Sonication and Multiplex Polymerase Chain Reaction
Published on: December 3, 2017
C-reactive protein: a valuable acute investigation. A case of pneumococcal meningitis presenting as ankle pain
1Musculoskeletal Research Unit, University of Edinburgh, Teviot Place, Edinburgh, EH8 9AG. jimhuntley@doctors.org.uk
Abstract:
A case is presented in which the decision to admit and treat an adult with musculoskeletal pain and pyrexia was based on her markedly raised c-reactive protein (CRP). At the time of admission she was apyrexial and the CRP was the only haematological investigation that was out of the normal range. She subsequently became precipitously septic with pneumococcal bacteraemia and meningitis. The CRP is an important investigation for emergency departments.
Related Concept Videos
Pneumonia III: Complications and Assessment
Pericarditis II: Clinical Features and Diagnostic Tests
Rheumatic Heart Disease II: Clinical Manifestations and Diagnostic Studies
Acute Pyelonephritis I: Introduction
Atypical Pneumonia
Bacterial Meningitis I: Introduction

