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Updated: Aug 16, 2026

Optimized Management of Endovascular Treatment for Acute Ischemic Stroke
Published on: January 18, 2018
[Interventional endovascular therapy (stenting) for residual stenosis after lysis of the basilar artery]
S Boy1, K Isenhardt, K Gardill
1Neurologische Klinik, Klinikum Aschaffenburg.
Insights
Intra-arterial thrombolysis and endovascular therapy offer excellent outcomes for acute basilar artery occlusion. Early stenting may be beneficial for residual stenosis after successful lysis.
Area of Science:
- Neurology
- Vascular Medicine
- Interventional Cardiology
Background:
- Basilar artery thrombosis carries a high mortality rate despite current treatments.
- Atherosclerotic stenosis is a likely precursor to acute basilar artery occlusion.
Observation:
- Three cases of acute basilar artery occlusion were treated with intra-arterial thrombolysis.
- Successful endovascular therapy followed thrombolysis in all reported cases.
Findings:
- Excellent clinical outcomes were achieved in all three patients.
- Acute thrombosis likely originated from pre-existing atherosclerotic stenoses.
Implications:
- Intra-arterial thrombolysis combined with endovascular therapy is a viable treatment for basilar artery occlusion.
- Early stenting could be a valuable strategy for managing residual stenosis post-thrombolysis.
Abstract:
Despite the introduction of local thrombolytic therapy, there is still a very high mortality rate in basilar thrombosis. We report three cases of successful intra-arterial thrombolysis of acute basilar artery occlusion and consecutive interventional endovascular therapy. In all cases, the acute thrombosis of the basilar artery probably developed from preexisting atherosclerotic stenoses. The clinical outcomes were excellent. We discuss early consecutive stenting as a possible therapeutic option in cases of residual stenosis after successful intra-arterial lysis of basilar artery occlusion.
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