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Initial depression and subsequent drinking during alcoholism treatment.

Kenneth R Conner1, Silva Sorensen, Kenneth E Leonard

  • 1Center for the Study and Prevention of Suicide, University of Rochester School of Medicine and Dentistry, 300 Crittenden Boulevard, Rochester, New York 14642, USA. kenneth_conner@urmc.rochester.edu

Journal of Studies on Alcohol
|July 29, 2005
PubMed
Summary

Elevated depressive symptoms in individuals entering alcoholism treatment predict increased drinking intensity and frequency in the initial treatment month. Early interventions may improve outcomes for those with depression.

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Area of Science:

  • Psychiatry
  • Addiction Medicine
  • Clinical Psychology

Background:

  • Alcoholism treatment often involves individuals with co-occurring depressive symptoms.
  • Depression can significantly impact treatment response and drinking outcomes in alcoholism.

Purpose of the Study:

  • To investigate the influence of depression at treatment entry on drinking patterns throughout alcoholism treatment.
  • To understand how initial depressive symptoms affect the trajectory of drinking during therapy.

Main Methods:

  • Analysis of the Project MATCH dataset, a large, multisite randomized trial for alcoholism.
  • Cross-lagged path analyses examined depression, drinking intensity, and drinking frequency over the 3-month active treatment phase.
  • 1,450 subjects (76% male, 24% female) were included, controlling for age, gender, race, and treatment assignment.

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Main Results:

  • Depression at treatment entry was associated with more intense and frequent drinking during the first month of treatment.
  • The predictive relationship between depression and drinking diminished in the second and third months of treatment.

Conclusions:

  • Individuals with higher depression levels at the start of alcoholism treatment may experience a delayed benefit.
  • Interventions targeting early treatment success for depressed individuals are warranted to improve engagement and retention.
  • Further research is needed on the long-term, bidirectional links between depression and drinking post-treatment.