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Updated: Aug 16, 2026

Electrophysiological Methods to Assess Peripheral Pain Block in an Anesthetized Rat
Published on: November 21, 2025
Lack of pain reduction by a vibrating local anesthetic attachment: a pilot study
Minori Saijo1, Emiko Ito, Tatsuya Ichinohe
1Department of Dental Anesthesiology, Tokyo Dental College, Chiba, Japan. okudam@tdc.ac.jp
Abstract:
A vibrating dental local anesthesia attachment (Vibraject, LLC, Calif) based on the concept of the gate-control theory has been used in clinical practice. The theoretical advantage of the vibrating needle is that it reduces the injection pain. We evaluated the effectiveness of Vibraject in combination with an electrical injection device. Injections were given into the alveolar mucosa adjacent to the root apex of the maxillary lateral incisor in 10 volunteers. Vibraject was randomly applied to either the left or right side of the injection. No statistically significant decrease in pain scores was found at needle insertion or anesthetic injection. The clinical efficacy of Vibraject remains controversial.
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