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Related Experiment Video

Updated: Jul 27, 2026

Whole-mount Immunohistochemical Analysis for Embryonic Limb Skin Vasculature: a Model System to Study Vascular Branching Morphogenesis in Embryo
09:53

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Published on: May 20, 2011

Nevus roseus: a distinct vascular birthmark.

Rudolf Happle1

  • 1University of Marburg, Deutschhausstr. 9, D-35033 Marburg, Germany. happle@med.uni-marburg.de

European Journal of Dermatology : EJD
|July 29, 2005
PubMed
Summary

A new term, nevus roseus, is proposed for a distinct light-red birthmark. This vascular malformation is associated with phacomatosis pigmentovascularis type III, differentiating it from nevus flammeus.

Area of Science:

  • Dermatology
  • Medical Genetics

Background:

  • Nevus flammeus, a dark vascular birthmark, is a key feature of phacomatosis pigmentovascularis type II (phacomatosis cesioflammea).
  • Distinguishing between various vascular birthmarks is crucial for accurate diagnosis and classification.

Observation:

  • A distinct lateralized, light-red or pale-pink telangiectatic birthmark, termed nevus roseus, has been observed.
  • This birthmark differs in color and presentation from the darker nevus flammeus.

Findings:

  • Nevus roseus is proposed as a distinct entity, not merely a color variant of nevus flammeus.
  • Nevus roseus is identified as a characteristic feature of phacomatosis pigmentovascularis type III (phacomatosis spilorosea).
  • Nevus roseus should be differentiated from midline salmon patches and broadly categorized as a capillary malformation.

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Implications:

  • The proposed term 'nevus roseus' aids in classifying specific vascular birthmarks.
  • Recognition of nevus roseus refines the diagnostic criteria for phacomatosis pigmentovascularis type III.
  • This classification improves understanding of distinct vascular malformations and associated syndromes.