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[Rheumatoid arthritis].

J Strunk1, U Lange, U Müller-Ladner

  • 1Lehrstuhl für Innere Medizin mit Schwerpunkt Rheumatologie der Justus-Liebig Universität Giessen, Abteilung für Rheumatologie und Klinische Immunologie, Kerckhoff-Klinik Bad Nauheim.

Deutsche Medizinische Wochenschrift (1946)
|July 29, 2005
PubMed
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[Diagnosis and treatment of ANCA-associated vasculitis : S3 guideline of the German Society for Rheumatology and Clinical Immunology e. V. (DGRh) and German Society for Internal Medicine e. V. (DGIM), German Society for Nephrology e. V. (DGfN), German Society for ENT Medicine and Head and Neck Surgery e. V. (DGHNO-KHC), German Ophthalmological Society e. V. (DOG), German Society for Neurology e. V. (DGN), German Society for Pneumology and Respiratory Medicine e. V. (DGP), German Society for Pathology e. V. (DGP), German Radiological Society, Society for Medical Radiology e. V. (DRG), Federal Association of German Pathologists, Federal Kidney Association e. V., German Rheumatism League Federal Association e. V.]

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[Diagnosis and treatment of ANCA-associated vasculitis : SHORT VERSION of the S3 guideline of the German Society for Rheumatology and Clinical Immunology e. V. (DGRh) and German Society for Internal Medicine e. V. (DGIM), German Society for Nephrology e. V. (DGfN), German Society for Otorhinolaryngology and Head and Neck Surgery e. V. (DGHNO-KHC), German Ophthalmological Society e. V. (DOG), German Society for Neurology e. V. (DGN), German Society for Pneumology and Respiratory Medicine e. V. (DGP), German Society for Pathology e. V. (DGP), German Radiological Society, Society for Medical Radiology e. V. (DRG), Federal Association of German Pathologists, Federal Kidney Association e. V., German Rheumatism League Federal Association e. V.]

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Novel anti-rheumatic drugs and advanced imaging improve rheumatoid arthritis treatment, aiming for remission. Early intervention with new therapies and supportive care enhances long-term patient outcomes.

Area of Science:

  • Rheumatology and Pharmacology

Background:

  • Rheumatoid arthritis (RA) management has shifted from symptomatic relief to achieving remission.
  • Early treatment is critical for improving long-term patient outcomes in RA.

Observation:

  • Advanced imaging techniques like MRI and high-frequency ultrasonography enable early detection of synovitis and joint destruction.
  • Established therapies include methotrexate, with newer drugs like leflunomide and combination therapies offering improved efficacy.

Findings:

  • The introduction of cytokine antagonists, such as TNF-a inhibitors, directly targets disease remission in RA.
  • Emerging therapeutic agents effectively modulate inflammatory and destructive processes in rheumatoid arthritis.

Implications:

  • Integrating novel drugs and imaging into RA management facilitates the goal of true remission.

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  • A comprehensive approach combining pharmacotherapy, physiotherapy, ergotherapy, and orthopedic surgery is essential for optimal RA patient care.