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Related Experiment Videos

Pachymetry before or after applanation tonometry: does it matter?

S Pourjavan1, C Deghislage, L Van Malderen

  • 1Dept. of Ophthalmology, University Hospitals of Leuven, Belgium.

Bulletin De La Societe Belge D'Ophtalmologie
|July 30, 2005
PubMed
Summary
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The order of central corneal thickness (CCT) and Goldmann applanation tonometry (GAT) measurements does not impact accuracy. This study found no significant difference in CCT or GAT results based on examination sequence.

Area of Science:

  • Ophthalmology
  • Optometry
  • Biomedical Engineering

Background:

  • Accurate intraocular pressure (IOP) measurement is crucial for glaucoma diagnosis and management.
  • Central corneal thickness (CCT) is a known factor influencing Goldmann applanation tonometry (GAT) readings.
  • The potential impact of sequential CCT and GAT measurements on their respective accuracy requires investigation.

Purpose of the Study:

  • To prospectively evaluate the influence of Goldmann applanation tonometry (GAT) on central corneal thickness (CCT) measurement accuracy.
  • To assess the influence of CCT measurement on GAT accuracy.
  • To determine if the sequence of CCT and GAT examinations affects measurement reliability.

Main Methods:

  • Prospective study involving 60 healthy volunteers.

Related Experiment Videos

  • Sequential measurements in the right eye: CCT--GAT--CCT.
  • Sequential measurements in the left eye: GAT--CCT--GAT.
  • Averaging of two tonometry and five pachymetry readings per examination.
  • Statistical analysis using Pearson correlation coefficients and Bland-Altman plots.

    • Main Results:

    • No statistically significant difference in mean CCT measurements before and after GAT in the right eye (p = 0.34, r = 0.98).
    • No statistically significant difference in mean GAT measurements before and after CCT in the left eye (p = 0.43, r = 0.86).
    • High correlation coefficients indicate consistency between sequential measurements.

    Conclusions:

    • The sequence of central corneal thickness (CCT) and Goldmann applanation tonometry (GAT) examinations does not significantly influence the accuracy of either measurement.
    • Clinical practice can proceed with either CCT or GAT measurement first without compromising reliability.
    • Findings support the robustness of both CCT and GAT measurement techniques regardless of examination order.