Related Experiment Video
Updated: Aug 16, 2026
Transuterine Fetal Tracheal Occlusion Model in Mice
Published on: February 5, 2021
Follow up of infants with congenital diaphragmatic hernia
1Department of Surgery, The University of Texas Houston Medical School, Houston, TX 77030, USA. Sonlee.D.West@uth.tmc.edu
Insights
Survival rates for congenital diaphragmatic hernia have improved, but long-term follow-up reveals significant pulmonary and extrapulmonary morbidities in survivors. This review identifies these associated health issues and their predictors.
Area of Science:
- Pediatric Surgery
- Neonatal Medicine
- Pulmonology
Background:
- Congenital diaphragmatic hernia (CDH) survival has increased due to advanced treatments.
- Long-term follow-up is crucial for understanding the full spectrum of CDH sequelae.
- Previously unrecognized pulmonary and extrapulmonary morbidities are emerging in CDH survivors.
Purpose of the Study:
- To review the associated morbidities in congenital diaphragmatic hernia survivors.
- To identify predictors of these long-term health issues in high-risk infants.
Main Methods:
- Literature review of studies on congenital diaphragmatic hernia survivors.
- Analysis of long-term outcomes, including pulmonary and extrapulmonary complications.
- Identification of risk factors and predictive markers for morbidities.
Main Results:
- CDH survivors face significant pulmonary challenges, including chronic lung disease.
- Extrapulmonary complications such as gastrointestinal, neurological, and cardiac issues are increasingly recognized.
- Predictors for these morbidities are being identified, aiding in risk stratification.
Conclusions:
- Improved survival in CDH necessitates a focus on managing long-term morbidities.
- Comprehensive, long-term follow-up is essential for early detection and management of pulmonary and extrapulmonary complications.
- Understanding predictors can guide personalized care and improve quality of life for CDH survivors.
Abstract:
Survival of patients with congenital diaphragmatic hernia has improved with the introduction of more sophisticated treatments. Long-term follow up has led to the recognition of pulmonary morbidity not previously recognized. In addition, extrapulmonary problems associated with the survival of these high-risk infants are now being identified. This review describes associated morbidities in congenital diaphragmatic hernia survivors and their predictors.
